摘要 目的:系统评价半夏白术天麻汤治疗高血压合并超重/肥胖的疗效和安全性。方法:全面检索中国知网(CNKI)、万方(WanFang)、维普(VIP)、中国生物医学文献服务系统(SinoMed)、PubMed、EMbase、the Cochrane Library、Web of Science及临床试验注册平台,搜集半夏白术天麻汤治疗高血压合并超重/肥胖的随机对照试验(RCT)。采用RevMan
摘要 目的:分析近10年经方治疗冠心病研究领域的发展现状、研究热点和未来趋势。方法:检索中国知网数据库(CNKI)中2011—2021年收录的经方治疗冠心病相关期刊文献,运用CiteSpace可视化软件,对该领域内地域、机构、作者及关键词绘制知识图谱并对其进行分析。结果:共纳入479篇文献,相关研究主要分布在北方地区,主要研究机构为南京中医药大学无锡附属医院(7篇)、辽宁中医药大学(4篇)、辽宁
摘要 目的:基于网络药理学、分子对接探讨邓氏温胆汤治疗动脉粥样硬化(AS)的潜在分子机制及靶点,并进行实验验证。方法:从中药系统药理学数据库和分析平台(TCMSP)中获取邓氏温胆汤的活性成分及相应靶点。下载GSE28829和GSE4329,鉴定早期和晚期AS斑块之间的差异表达基因,并对差异表达基因进行富集分析。通过多种生物信息学算法确定AS的最佳候选基因,并与邓氏温胆汤相关靶点相交,从而确定关键
摘要 目的:基于网络药理学与分子对接技术分析二仙汤治疗绝经后冠心病共病骨质疏松的作用机制。方法:利用中药系统药理学数据库与分析平台获取二仙汤靶蛋白,从GeneCards和OMMI数据库中获得绝经后骨质疏松与绝经后冠心病相关蛋白,将药物与疾病靶点取交集;通过Cytoscape软件、STRING 数据库以及DAVID 数据库筛选二仙汤治疗绝经后冠心病共病骨质疏松的关键靶蛋白、靶点以及通路。最后,通过
摘要 目的:探讨麝香保心丸通过拮抗心肌细胞凋亡改善异丙肾上腺素(ISO)诱发的心肌梗死大鼠心肌纤维化的作用。方法:30只SD雄性大鼠随机分成对照组、模型组(ISO组)、麝香保心丸组。以腹腔注射ISO[50 mg /(kg·d)]2 d 构建心肌梗死大鼠模型,麝香保心丸组给予麝香保心丸45 mg /(kg·d) 灌胃,ISO组和对照组同时给予等量的蒸馏水灌胃。干预6周后处死大鼠,以 Masson
摘要 目的:观察青藤碱(SIN)对慢性心力衰竭(CHF)大鼠氧化应激和心肌纤维化的改善作用,并探究其对Janus蛋白酪氨酸激酶2(JAK2)/信号转导和转录激活子3(STAT3)/细胞因子信号转导抑制因子1(SOCS1)信号通路的作用。方法:利用缩窄腹主动脉法构建CHF大鼠模型,随机分为模型组、卡托普利组(6.75 mg/kg)、SIN低剂量组(5 mg/kg)、SIN中剂量组(10 mg/kg
摘要 目的:探讨细胞周期蛋白依赖性激酶7(CDK7)抑制剂THZ1对射血分数降低的心力衰竭(HFrEF)小鼠心肌肥大和心脏功能的保护作用并探讨其作用机制。方法:将10周龄雄性C57BL/6小鼠成年应用永久性冠状动脉结扎术诱导HFrEF小鼠模型(HFrEF组,12只),12只小鼠接受假手术(sham组)。54只小鼠行冠状动脉结扎术,将存活的36只小鼠分为HFrEF组、THZ1组、THZ1+Coli
摘要 目的:探讨Ⅲ型纤连蛋白域蛋白5(FNDC5)过表达对老年慢性心力衰竭(CHF)大鼠氧化应激、细胞凋亡及腺苷酸活化蛋白激酶(AMPK)/沉默信息调控因子1(SIRT1)信号通路的影响。方法:以腹腔注射阿霉素建立老年CHF大鼠模型,将造模成功的老年CHF大鼠随机分为模型组(CHF组)、空载体慢病毒组(Lv-NC组)、FNDC5过表达慢病毒组(Lv-FNDC5组)、FNDC5过表达慢病毒+AMP
Research Progress of Yangxinshi Tablets in the Treatment of Dual-cardiac Related Diseases WANG Zhizheng1, YANG Jie2, YANG Lei1, YANG Chuanhua2 1.Shandong University of Traditional Chinese Medicine,
Exploring the Mechanism of Ferroptosis in Atherosclerosis Based on the Theory of "Blood Stasis" GAO Kun1, LI Lizhi 2, WANG Lianhua1 1.Shanxi University of Chinese Medicine, Taiyuan 030024, Shanxi, C
Research Progress on In-stent Restenosis after Drug-eluting Stent Implantation in Patients with Hyperhomocysteinemia CHEN Haitao1, GUO Jiqiang2, GAO Yuping1 1.Shanxi Medical University, Taiyuan 0300
The Prognostic Predictive Value of Hemoglobin and Serum Protein Levels in Elderly Patients with Unstable Angina Pectoris with Normal Left Ventricular Function after PCI LI Hua, LIU Peilin, DONG Danda
Tei Index and Free Triiodothyronine on Predicting Long-term Prognosis in Patients with Dilated Cardiomyopathy CHANG Xuewei1, SHEN Yu1, ZHENG Weifeng1, GU Yunfei1, WEI Jinghan2, WEI Yidong3 1.Luoyang
Relationship between Lp-PLA2 and the Severity of Coronary Stenosis and Prognosis in Patients with Coronary Heart Disease LYU Dongchen, HUANG Xiao, YANG Qian, YUAN Yu The First Affiliated Hospital of
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Relationship between Central Venous-arterial Carbon Dioxide Difference and Postoperative Cognitive Dysfunction in Patients with Acute Aortic Dissection WANG Lei, JIANG Zhang, ZHANG Wenxiu, DING Lili,
Effect of Timing of IABP Application for Emergency PCI on Inflammatory Factors, Left Ventricular Function, and Prognosis in Patients with ACS Combined with Cardiogenic Shock XU Kai1, LIU Li2, QIN Guo
Effect of Transversus Abdominis Plane Block on Perioperative Adverse Cardiovascular Events in Diabetic Patients Undergoing Gynecological Laparoscopic Surgery ZHAO Peizhong1, ZHANG Ruilin2, ZHANG Linz
Single-center Analysis of Changes for the Treatment of Atrial Fibrillation in the Cardiology Department from 2008 to 2019 ZHANG Xi1, LI Zhan2, WEI Yanjin3 1.Medical College of Qingdao University, Li
Efficacy of Tongdu Tiaoshen Acupuncture Method Combined with Ginkgo Diterpene Lactone Meglumine Injection in Patients with Cerebral Infarction and Its Influence on Serum NLRP3 and IL-1β CHEN Chong, S
Clinical Study on the Treatment of Shoulder-Hand Syndrome with Stick Acupuncture Combined with Rehabilitation Training YANG Yang1, LI Haiying1, YANG Yanfang2, SHANG Shuhui1, YANG Xiaoqing1 1.Handan
Exploration of the Treatment of Unstable Angina Pectoris Based on the "Qi Street Theory" LU Jieming1,2, QIAN Longxin1, WANG Jie3, TAN Ling3, LI Shusen4, LONG Linzi2, QU Hua2, FU Changgeng2,5 1.Beiji
Exploring the Mechanism and Prevention and Treatment Strategies of Microvascular Angina Pectoris Based on the "Qi-Blood-Venation" Theory CAI Yongyuan1, LI Mengran2, Hou Zhonghao3, NIU Tianfu4 1.Guan
The Treatment of Tachycardia in "Long COVID" from "Residual Heat" GUAN Qiaoyan1, BAO Songyu1, LI Siming2 1.Shanxi University of Chinese Medicine, Taiyuan 030024, Shanxi, China; 2.Cardiovascular Unit
A Case Report:Deng Yue's Treating Coronary Heart Disease Complicated with Carotid Artery Stenosis by the Huotan Jiedu Tongluo Formula HAN Danxu1, DENG Yue2 1.Changchun University of Chinese Medicine
Acute Inferior Myocardial Infarction Caused by Anti-Cardiolipin Syndrome Secondary to Systemic Lupus Erythematosus Treated by Thrombus Aspiration Combined with Traditional Chinese Medicine:a Case Repo
Professor Shi Zaixiang Treating Anorexia Nervosa Complicated with Sinus Bradycardia and Syncope:a Case Report GAO Wei1, CUI Hailan2, SHI Zaixiang2 1.Beijing Chaoyang District Balizhuang Community He